Department Profit and Loss reports rely on your using Departments as profit centers. You might have Sales and Service as Departments, each with their income and expense.
This is a tall ask and generally requires consensus to create and use your Departments. You might also turn on the Department Mandatory setting found in Employee Prefs.
Using Departments for another purpose is common and Department Prefs extend this. Using Department Prefs you might change to use this setting for Freight Terms entry.